Serum visfatin, resistin levels and inflammation markers in psoriasis patients

Psoriasis is a common chronic inflammatory skin condition that varies in severity. associated with complex disorders, which incorporate metabolic syndrome, obesity and impaired glucose tolerance. Adipose tissue secretes several hormones cytokines, particular visfatin resistin could be involved the development of psoriasis by acting as pro-inflammatory or immunoregulatory factors. The aim this work was to evaluate serum level well high-sensitivity C-reactive protein (hs-CRP) erythrocyte sedimentation rate (ESR) psoriatic patients. study included 43 healthy individuals 45 patients divided into three groups mild, moderate severe clinical degrees disease assessed Area Severity Index (PASI). results showed significant increase concentration visfatin, resistin, ESR hs-CRP patient comparison control group. highest indicators observed group compared mild groups. significance studied biomarkers severity analyzed. Keywords: rate, high sensitivity protein, psoriasis,